Thermo Fisher Scientific SUR1 Monoclonal Antibody (N289/16), APC
SUR1 단백질을 검출하는 Thermo Fisher Scientific의 마우스 단클론 항체로, APC 형광체가 결합된 제품입니다. WB, IHC, ICC/IF에 사용 가능하며, 높은 특이성과 재현성을 제공합니다. 단백질 G 정제, 보존제 무첨가, 연구용으로 적합합니다.
- 카탈로그번호
- MA545558
- 판매단위
- pk
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Thermo Fisher Scientific SUR1 Monoclonal Antibody (N289/16), APC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Hamster, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N289/16 |
| Immunogen | Fusion protein amino acids 1548–1582 (cytoplasmic C-terminus) of rat SUR1 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.46 mM phosphate / 2.48 mM MES, pH 7.4, with 2 mM EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932012 |
Additional Formats
- Unconjugated (MA5-27660)
- FITC (MA5-45559)
- PE (MA5-45561)
- PerCP (MA5-45560)
- Request custom conjugation
Product Specific Information
- 1 µg/mL of MA5-45558 was sufficient for detection of SUR1 in 20 µg of mouse brain membrane lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- Detects approximately 160 kDa.
- Does not cross-react with SUR2B.
- This antibody was formerly sold as clone S289-16.
Target Information
The protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily. ABC proteins mediate transport of various molecules across cellular membranes and are grouped into seven subfamilies. This protein is part of the MRP subfamily related to multi-drug resistance. It modulates ATP-sensitive potassium channels and insulin release. Mutations are linked to hyperinsulinemic hypoglycemia of infancy and type II diabetes mellitus. Alternative splicing has been observed but not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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