
Thermo Fisher Scientific Phospho-MCM2 (Ser40, Ser41) Polyclonal Antibody
Ser40, Ser41 부위의 인산화된 MCM2 단백질을 인식하는 Rabbit Polyclonal Antibody. 인간 및 생쥐 반응성. IHC 및 IHC(P) 실험에 적합하며 항원 친화 크로마토그래피로 정제. DNA 복제 및 세포주기 연구용.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic di-phosphorylated peptide representing a portion of Human MCM2 surrounding Serines 40 and 41 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Predicted to react with Rat, Xenopus laevis, Xenopus tropicalis, Bovine, Dog, Horse, Rabbit, Guinea pig, Pig, Panda, Orangutan, Monkey, and Gorilla (based on 100% sequence identity)
Target Information
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2, also known as CDCL1, mitotin, and BM28, is a human nuclear protein crucial for the cell cycle, participating in the initiation of DNA replication and cell division. It is similar to early S-phase proteins and mapped to chromosome 3q21. CDCL1 has been suggested as a candidate oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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