Thermo Fisher Scientific PDGFRA Monoclonal Antibody (16A1), APC
인간 PDGFRA(CD140a)를 인식하는 마우스 단클론 항체로, APC로 표지되어 유세포분석(Flow Cytometry)에 적합합니다. 세포막 외부 에피토프를 인식하며, 4°C 암소 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): 10 µL / 1×10⁶ cells
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 16A1 |
| Immunogen | CD140a-transfected NIH 3T3 cells |
| Conjugate | APC (Allophycocyanin) |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153447 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor. It is widely expressed on various mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in different tumor types.
Target Information
PDGFRA is a cell surface receptor tyrosine kinase that binds members of the platelet-derived growth factor family, which are mitogens for mesenchymal-origin cells. The receptor can form homodimers or heterodimers (with PDGFRB), depending on the ligand. Knockout studies indicate PDGFRA’s essential role in kidney development, as heterozygous mice show defective renal phenotypes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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