Thermo Fisher Scientific CD142 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.1 µg/mL

-

Flow Cytometry (Flow)

2.5 µg/1x10^6 cells

-

Immunoprecipitation (IP)

25 µg/mL

-

Product Specifications

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Coagulation Factor III/Tissue Factor Ala29-Glu251 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD142,uniProtId:P20352-1,ncbiNodeId:10090,antigenRange:29-251,antigenLength:294,antigenImageFileName:PA5-47465_CD142_P20352-1_Goat.svg,antigenImageFileNamePDP:PA5-47465_CD142_P20352-1_Goat_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2609244

Product Specific Information

In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human Coagulation Factor III is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.