Thermo Fisher Scientific PFKM Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, mouse brain, rat brain
• Predicted reactivity: Mouse (96%), Rat (94%), Xenopus laevis (89%), Dog (97%), Pig (95%), Chicken (88%), Bovine (96%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.
The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells.
Unlike other proteins in this family, this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions.
The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.