Thermo Fisher Scientific GORAB Monoclonal Antibody (OTI1E3), TrueMAB
GORAB 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(Paraffin)에 적합. Human, Mouse, Rat, Dog 시료에 반응하며, Affinity chromatography로 정제됨. PBS/BSA/glycerol buffer에 보관되며 -20°C에서 안정적.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E3 |
| Immunogen | Human recombinant protein fragment (aa 35–394 of human GORAB) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TCEB1, also known as protein elongin C, is a subunit of the transcription factor B (SIII) complex. This complex, composed of elongins A/A2, B, and C, activates elongation by RNA polymerase II by suppressing transient pausing at multiple sites within transcription units.
Elongin A acts as the transcriptionally active component, while elongins B and C serve as regulatory subunits. Elongin A2 is testis-specific and forms a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, thereby inhibiting transcription elongation.
Western blot analysis using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against distinct regions of this protein confirmed consistent molecular weights in testing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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