Thermo Fisher Scientific GORAB Monoclonal Antibody (OTI4F11), TrueMAB
GORAB 단백질을 인식하는 Mouse monoclonal antibody(OTI4F11)로, Western blot 및 IHC(P) 검증 완료. Human 시료 반응성, Affinity chromatography 정제. -20°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–394 of human GORAB produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TCEB1, also known as protein elongin C, is a subunit of the transcription factor B (SIII) complex. The SIII complex consists of elongins A/A2, B, and C, and activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase. Elongin A serves as the transcriptionally active component, while elongins B and C act as regulatory subunits. Elongin A2 is specifically expressed in the testis and forms a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, inhibiting transcription elongation. Western blots using two distinct antibodies (P100962-T200 and P100963_P050 / P100963_P100) targeting unique regions of this protein confirm consistent molecular weight results.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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