Thermo Fisher Scientific LMAN1 Polyclonal Antibody
LMAN1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체로, Western blot 및 면역형광(ICC/IF)에 적합합니다. 인간, 생쥐, 랫트 시료에서 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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- PA1074
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 3 publications |
| Immunocytochemistry (ICC/IF) | 1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues F(159) D S F D N D G K K N N P A I(173) of rat ERGIC-53 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2265708 |
Product Specific Information
PA1-074 detects ERGIC-53 in rat, mouse, and human samples.
This antibody has been successfully used in Western blot and immunofluorescence (ICC/IF) procedures.
By Western blot, it detects a ~57.5 kDa protein representing ERGIC-53 in rat brain samples.
The immunogen is a synthetic peptide corresponding to residues F(159) D S F D N D G K K N N P A I(173) of rat ERGIC-53, conserved in mouse and human.
The immunizing peptide (Cat. # PEP-277) is available for use in neutralization and control experiments.
Target Information
The LMAN1 protein is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi apparatus, recycling between these compartments.
It functions as a mannose-specific lectin and belongs to a family of plant lectin homologs in the secretory pathway of animal cells.
Mutations in this gene are associated with a coagulation defect, specifically combined factor V-factor VIII deficiency, a rare autosomal recessive disorder characterized by reduced levels of both coagulation factors V and VIII.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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