Thermo Fisher Scientific PTPRT Polyclonal Antibody
PTPRT 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체. 인간 및 마우스 시료에 반응하며, IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human Protein tyrosine phosphatase, receptor type, T |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2636021 |
Product Specific Information
This antibody detects endogenous levels of total PTPRT protein.
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
PTPRT is a receptor-type PTP with an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains. The extracellular region includes a meprin-A5 antigen-PTP domain, Ig-like, and fibronectin type III-like repeats.
The domain structure and expression pattern of the mouse homolog suggest roles in both signal transduction and cellular adhesion in the central nervous system.
Two alternatively spliced transcript variants encoding distinct proteins have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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