Thermo Fisher Scientific PSMD11 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Product Specifications

Product Specific Information

This antibody detects endogenous levels of total PSMD11 protein.

Target Information

The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.

• The 20S core consists of four rings of 28 non-identical subunits (two rings of seven alpha subunits and two rings of seven beta subunits).
• The 19S regulator includes a base (with six ATPase subunits and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits).
  Proteasomes are widely distributed in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent process within a non-lysosomal pathway.
  A key function of the immunoproteasome is the processing of class I MHC peptides. PSMD11 is a non-ATPase subunit of the 19S regulator.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.