Thermo Fisher Scientific Phospho-RelB (Ser552) Recombinant Rabbit Monoclonal Antibody (RelBS552-A7), FITC
RelB 인산화(Ser552) 부위를 인식하는 재조합 토끼 단클론 항체로, FITC 형광 표지되어 유세포분석(Flow Cytometry)에 최적화됨. 인산화 RelB 검출에 특이적이며, 인간 및 생쥐 시료 모두에 반응. 단백질 A/G 정제, PBS+BSA 완충액 저장.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RelBS552-A7 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser552 of human phospho RelB |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896967 |
Additional Formats
- Unconjugated (Cat. MA5-37030)
- APC (Cat. MA5-37033)
- PE (Cat. MA5-37031)
- Custom conjugation available upon request
Target Information
The NFκB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNA-binding subunit is functionally related to c-Rel p75 and RelB p68. The p50 subunit was initially believed to be a unique protein derived from the amino-terminus of a precursor designated p105. A second protein, p52 (previously referred to as p49), has been identified that can act as an alternative NFκB subunit. RelB does not bind with high affinity to NFκB sites, but heterodimers between RelB and p50 bind with comparable affinity to p50 NFκB homodimers. RelB/p50 heterodimers, unlike NFκB heterodimers, can transactivate transcription of promoters containing κB binding sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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