Thermo Fisher Scientific ER81 Polyclonal Antibody
ER81 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로, WB 및 IHC(P) 분석에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 항원 친화 크로마토그래피로 정제되었습니다. 핵 및 세포질 위치 단백질 검출에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of human ER81 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Mouse brain
- Cellular location: Nuclear, Cytoplasmic
Target Information
ETV1 (ER81): Ets variant gene 1.
Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All Ets proteins recognize this core sequence but interact with unique flanking sequences.
ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'.
ER81 is highly expressed in brain, testis, lung, and heart, and moderately expressed in spleen, pancreas, colon, and small intestine. During development, ER81 shows unique expression patterns suggesting its role in organogenesis.
ERK-1 activates ER81 transcriptional activity, while MAPKAP kinase 2 inhibits it.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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