Thermo Fisher Scientific c-Maf Recombinant Rabbit Monoclonal Antibody (BLR045F)
Thermo Fisher Scientific의 c-Maf Recombinant Rabbit Monoclonal Antibody (BLR045F)는 인간 및 생쥐 시료에 반응하며, WB, IHC, ICC/IF, IP 등 다양한 응용에 적합합니다. HEK293 세포에서 발현된 정제된 액상 항체로, 4°C에서 보관하며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 - 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 - 1:500 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR045F |
| Immunogen | Peptide representing a region between residues 125 and 175 of human MAF bZIP transcription factor (c-Maf) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1000 µg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 7.8 to 8.6 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Target Information
c-Maf is the cellular counterpart of oncogenic v-maf and belongs to the family of basic region leucine zipper domain transcription factors. The leucine-zipper domain mediates interaction with LRPICD. Two forms of human c-maf mRNA exist: c-maf-long and c-maf-short. Identified in the genome of the acute transforming avian retrovirus AS42, c-maf targets IL-4 in Th2 cells, crystalline genes in lens fiber cells, insulin gene in islets, and p53 and L7. It regulates Th2 differentiation and lineage-specific hematopoiesis. c-maf acts as a transcription factor for IL-10 expression in LPS-activated macrophages. Chromosomal aberrations involving maf are found in some forms of multiple myeloma. Expression is observed in myeloma cell lines and resting monocytes/macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항원 이미지: A700-045_c-MAF_O75444-2_Rabbit.svg, A700-045_c-MAF_O75444-2_Rabbit_PDP.jpeg)
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