Thermo Fisher Scientific PPARGC1B Recombinant Rabbit Monoclonal Antibody (ARC2136)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC2136

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 924-1023 of human PGC1 beta (NP_5735703) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PPARGC1B,uniProtId:Q86YN6-1,ncbiNodeId:9606,antigenRange:924-1023,antigenLength:1023,antigenImageFileName:MA5-38114_PPARGC1B_Q86YN6-1_Rabbit.svg,antigenImageFileNamePDP:MA5-38114_PPARGC1B_Q86YN6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.48 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2898032

Product Specific Information

Positive Samples: HeLa, SH-SY5Y, Rat testis

Immunogen sequence: VFGEIEECEV LTRNRRGEKY GFITYRCSEH AALSLTKGAA LRKRNEPSFQ LSYGGLRHFC WPRYTDYDSN SEEALPASGK SKYEAMDFDS LLKEAQQSLH

Target Information

PGC-1 beta is a tissue specific co-activator that enhances the activity of estrogen receptor alpha. The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner. Ectopic expression of this protein has been shown to lead to increased mitochondrial number and basal oxygen consumption.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.