Thermo Fisher Scientific PPARGC1B Recombinant Rabbit Monoclonal Antibody (ARC2136)
Thermo Fisher의 PPARGC1B 재조합 토끼 단클론 항체(ARC2136)는 인간 및 랫트 시료에 반응하며, Western blot과 ELISA에 적합합니다. HEK293 세포에서 발현된 고순도 항체로, PGC-1β 단백질의 특정 서열(aa 924–1023)을 인식합니다. 연구용으로 안정적이고 재현성 높은 결과를 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2136 |
| Immunogen | Synthetic peptide corresponding to amino acids 924–1023 of human PGC1 beta (NP_5735703) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.48 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898032 |
Product Specific Information
- Positive Samples: HeLa, SH-SY5Y, Rat testis
- Immunogen Sequence:
VFGEIEECEV LTRNRRGEKY GFITYRCSEH AALSLTKGAA LRKRNEPSFQ LSYGGLRHFC WPRYTDYDSN SEEALPASGK SKYEAMDFDS LLKEAQQSLH
Target Information
PGC-1 beta is a tissue-specific co-activator that enhances the activity of estrogen receptor alpha.
The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner.
Ectopic expression of this protein has been shown to lead to increased mitochondrial number and basal oxygen consumption.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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