Thermo Fisher Scientific Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody (ARC2142)
Cytokeratin 6 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ELISA 등에 적합합니다. 인간, 생쥐, 랫트 반응성을 가지며 높은 특이성과 재현성을 제공합니다. HEK293 세포에서 발현된 IgG 형 항체로 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2142 |
| Immunogen | Synthetic peptide within amino acids 1–100 of human Cytokeratin 6 (KRT6, UniProt ID: P02538) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.3) with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898038 |
Product Specific Information
- Positive Samples: 5637, A-431
- Immunogen sequence:
MASTSTTIRS HSSSRRGFSA NSARLPGVSR SGFSSVSVSR SRGSGGLGGA CGGAGFGSRS LYGLGGSKRI SIGGGSCAIS GGYGSRAGGS YGFGGAGSGF
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region, also known as hyperproliferation-related keratins. Keratin 6 is found in hair follicles and suprabasal cells of various internal stratified epithelia, as well as in epidermis under both normal and hyperproliferative conditions. Epidermal injury induces keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas, and its expression is associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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