Thermo Fisher Scientific IGLC2 Monoclonal Antibody (5E12B9)
IGLC2 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체. Western blot, IHC, ELISA 등 다양한 응용에 적합. 고순도 Protein G 정제, 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5E12B9 |
| Immunogen | Purified recombinant fragment of human IGLC2 (AA: 1–106) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787399 |
Product Specific Information
MA5-31776 has been tested in indirect ELISA.
Target Information
IGLC2 is involved in the constant region of immunoglobulin heavy chains. Immunoglobulins (antibodies) are membrane-bound or secreted glycoproteins produced by B lymphocytes.
In the recognition phase of humoral immunity, membrane-bound immunoglobulins act as receptors that, upon antigen binding, trigger clonal expansion and differentiation of B lymphocytes into plasma cells.
Secreted immunoglobulins mediate the effector phase of humoral immunity, leading to antigen elimination.
Each immunoglobulin has two antigen-binding sites formed by the variable domains of one heavy and one light chain.
The variable domains are assembled by V-(D)-J rearrangement and undergo somatic hypermutation, enabling affinity maturation after antigen exposure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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