Thermo Fisher Scientific PEX7 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:20–1:50

Product Specifications

Product Specific Information

Immunogen sequence:
MSAVCGGAAR MLRTPGRHGY AAEFSPYLPG RLACATAQHY GIAGCGTLLI LDPDEAGLRL FRSFDWNDGL FDVTWSENNE HVLITCSGD

• Highest antigen sequence identity to orthologs:
  • Mouse: 81%
  • Rat: 80%

Target Information

This gene encodes the cytosolic receptor for the set of peroxisomal matrix enzymes targeted to the organelle by the peroxisome targeting signal 2 (PTS2).
Defects in this gene cause peroxisome biogenesis disorders (PBDs), which are characterized by multiple defects in peroxisome function.
There are at least 14 complementation groups for PBDs, with more than one phenotype observed in specific groups.
Although clinical features vary, all PBD patient cells exhibit defects in import of one or more classes of peroxisomal matrix proteins.
Defects in this gene are associated with:

• PBD complementation group 11 (PBD-CG11)
• Rhizomelic chondrodysplasia punctata type 1 (RCDP1)
• Refsum disease (RD)

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.