Thermo Fisher Scientific TRIM5 alpha Monoclonal Antibody (3B11H2)
인간 TRIM5α 단백질을 인식하는 마우스 단클론 항체로 Western blot, IHC, ELISA에 사용 가능. 비결합형 액상 형태로 제공되며 4°C 또는 -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B11H2 |
| Immunogen | Purified recombinant fragment of human TRIM5 alpha expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10988356 |
Product Specific Information
MA5-15232 targets TRIM5α in indirect ELISA, IHC, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human TRIM5 alpha expressed in E. coli.
Target Information
The protein encoded by this gene belongs to the tripartite motif (TRIM) family, which includes three zinc-binding domains (a RING, a B-box type 1, and a B-box type 2) and a coiled-coil region.
This protein forms homo-oligomers via the coiled-coil region and localizes to cytoplasmic bodies. It functions as an E3 ubiquitin ligase, ubiquitinating itself to regulate subcellular localization and may play a role in retroviral restriction.
Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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