Thermo Fisher Scientific TIP60 Polyclonal Antibody
Human TIP60 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 실험에 사용 가능. Protein A로 정제된 액상 형태이며, 1 mg/mL 농도로 제공. PBS buffer에 0.05% sodium azide 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.25–1 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acids 480–530 of human TIP60 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540814 |
Target Information
TIP60 is a transcription factor originally isolated as an HIV-1 TAT-interactive protein, known to interact with the viral TAT protein that leads to HTATIP polyubiquitination and degradation. It belongs to the MYST family of histone acetyltransferases (HATs) and acts as a catalytic subunit of the NuA4 histone acetyltransferase complex, which activates transcription of select genes by acetylating nucleosomal histones H4 and H2A. TIP60 functions as a co-regulator of transcription factors and can either promote or suppress tumorigenesis. It plays a significant role in DNA repair, apoptosis, and signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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