Thermo Fisher Scientific PON1 Monoclonal Antibody (OTI2D4), TrueMAB
PON1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI2D4). Western blot, IHC, ICC/IF, Flow cytometry, ELISA에 적합. Human 시료 반응성. Affinity chromatography로 정제된 액상 형태로, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D4 |
| Immunogen | Full length human recombinant protein of human PON1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.97 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
The paraoxonase (PON) gene family in humans has three members: PON1, PON2, and PON3, located on chromosome 7q21.3–22.1.
PON1 is synthesized primarily in the liver and secreted into plasma, where it associates with high-density lipoproteins (HDL).
It hydrolyzes active metabolites of several organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon) and nerve agents such as sarin, soman, and VX.
PON1 polymorphism may contribute to neurodegeneration and is considered an independent risk factor for Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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