
Thermo Fisher Scientific BECN1 Monoclonal Antibody (OTI3F3), TrueMAB
BECN1 단백질을 표적하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, ICC/IF, Flow cytometry에 적합합니다. 인간 및 랫트 반응성을 가지며, 액상 형태로 제공됩니다. 자가포식 연구 및 PI3K 복합체 관련 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F3 |
| Immunogen | Full-length human recombinant protein of BECN1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.78 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Beclin 1 plays a central role in autophagy as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate.
Different PI3K complex forms (PI3KC3-C1 and PI3KC3-C2) are involved in multiple membrane trafficking pathways, including autophagosome initiation, maturation, and endocytosis.
Beclin 1 also contributes to antiviral host defense mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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