Thermo Fisher Scientific Oncostatin M Polyclonal Antibody
마우스 Oncostatin M을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody. Western blot, IHC, Neutralization 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 교차반응 <2%로 높은 특이성 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL | View publication |
| Neutralization (Neu) | 0.6–3.0 µg/mL | View publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant mouse OSM (Ala24–Arg206) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608554 |
Product Specific Information
- In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human OSM is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of antibody by the LAL method.
Target Information
Oncostatin M (OSM) is a growth and differentiation factor involved in neurogenesis, osteogenesis, and hematopoiesis. It is produced by activated T cells, monocytes, and Kaposi’s sarcoma cells, and can exert both stimulatory and inhibitory effects on cell proliferation. OSM promotes fibroblast, smooth muscle, and Kaposi’s sarcoma cell proliferation, while inhibiting some normal and tumor cell lines. It also induces cytokine release (IL-6, GM-CSF, G-CSF) from endothelial cells and enhances LDL receptor expression in hepatoma cells. Structurally and functionally related to LIF, IL-6, and CNTF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-47022_Oncostatin_M_P53347-1_Goat.svg)
(이미지: PA5-47022_Oncostatin_M_P53347-1_Goat_PDP.jpeg)
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