Thermo Fisher Scientific Phospho-NFATC2 (Ser330) Polyclonal Antibody
NFATC2 단백질의 Ser330 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Dot blot에서 1:500 희석으로 검증됨. 액상 형태로 공급되며 4°C 또는 -20°C에 보관. 면역 반응 조절 관련 연구용으로 적합.
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Applications
- Dot blot (DB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S330 of human NFATC2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10978054 |
Target Information
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response.
Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3).
These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors.
Another NFAT-related protein, NFAT5, differs from isoforms 1–4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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