Thermo Fisher Scientific Phospho-HGK (Ser629) Polyclonal Antibody
인간 HGK(MAP4K4)의 Ser629 인산화 부위를 인식하는 폴리클로날 항체입니다. Rabbit IgG 기반으로 제작되었으며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 연구용으로 스트레스 관련 MAPK 신호 경로 분석에 적합합니다.
- 판매단위
- pk
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Applications
- Dot blot (DB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S629 of human MAP4K4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2140974 |
Target Information
MAP4K4 (HGK) is a serine/threonine kinase that plays an important role in stress-activated MAPK core signaling pathways and the response to environmental stress and cytokines such as TNF-alpha. It acts upstream of the JUN N-terminal pathway and interacts with the SH3 domain of adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression is ubiquitous across tissue types; isoform 5 is more abundant in the brain, while isoform 4 predominates in liver, skeletal muscle, and placenta.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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