Thermo Fisher Scientific Phospho-4EBP1 (Thr36) Polyclonal Antibody
Phospho-4EBP1 (Thr36) 폴리클로날 항체로, 인간 단백질에 반응하며 토끼에서 생산되었습니다. 단백질 합성 조절 연구에 적합하며, Dot blot 등에 사용 가능합니다. Protein A 및 항원 친화 크로마토그래피로 정제되었습니다.
- 카탈로그번호
- PA512847
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- pk
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Applications
- Dot blot (DB)
Tested Dilution: 1:500
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T36 of human EIF4EBP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2097834 |
Product Specific Information
This antibody is predicted to react with bovine, mouse, and rat based on sequence homology.
Target Information
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. Phosphorylation in response to signals such as UV irradiation and insulin signaling causes dissociation from eIF4E and activation of mRNA translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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