Thermo Fisher Scientific MYOZ1 Monoclonal Antibody (OTI1C11), TrueMAB
MYOZ1 단백질을 인식하는 단클론 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat 시료에 반응하며, 동결건조 형태로 제공됩니다. 친화 크로마토그래피로 정제되었고, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- CF809013
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 106–299 of human MYOZ1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity that spans half the sarcomere length. MYOZ1 encodes a protein found in striated and cardiac muscle that binds to the titin Z1–Z2 domains and serves as a substrate of titin kinase. These interactions are critical for sarcomere assembly. Mutations in MYOZ1 are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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