Thermo Fisher Scientific CYTH2 Monoclonal Antibody (OTI4D9), TrueMAB
CYTH2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(P)에서 검증됨. Human, Mouse, Rat 반응성. Lyophilized 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 단백질 분류 및 세포막 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D9 |
| Immunogen | Full length human recombinant protein of human CYTH2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The CYTH2 gene encodes a member of the PSCD family, characterized by:
- N-terminal coiled-coil motif (homodimerization)
- Central Sec7 domain (guanine-nucleotide exchange activity)
- C-terminal pleckstrin homology (PH) domain (phospholipid interaction and membrane association)
Members of this family are involved in protein sorting and membrane trafficking regulation.
The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6, and shares 83% homology with CYTH1.
Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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