Thermo Fisher Scientific PITX3 Recombinant Rabbit Monoclonal Antibody (5H10L5)
PITX3 단백질(1-65 aa)에 특이적인 재조합 토끼 단클론 항체. 인간에 반응하며 마우스에서도 예측 반응. 높은 특이성과 민감도, 로트 간 일관성, 동물 유래 성분 없음. ICC/IF에 1–3 µg/mL로 사용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5H10L5 |
| Immunogen | Recombinant protein corresponding to amino acids 1–65 of human PITX3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532424 |
Product Specific Information
- Predicted to react with mouse based on sequence homology.
- Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generates ~25 kDa light chain and ~50 kDa heavy chain bands.
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone antibody DNA sequences from immunoreactive rabbits and select optimal clones for production.
- Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The PITX3 gene encodes a member of the RIEG/PITX homeobox family, belonging to the bicoid class of homeodomain proteins. Members act as transcription factors and are involved in lens formation during eye development. Mutations are associated with anterior segment mesenchymal dysgenesis and congenital cataracts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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