Thermo Fisher Scientific VPS34 Recombinant Superclonal Antibody (8HCLC)

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of a selection of multiple recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
These antibodies recognize multiple epitope sites on the target, providing higher detection sensitivity for low-abundance targets.
Each lot is produced with a defined mixture of light and heavy chains, ensuring reproducibility and eliminating biological variability typically associated with polyclonal antibody production.

Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.

Target Information

PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. It phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes.
PIK3C3 is involved in nutrient signaling to mTOR, autophagy, and intracellular trafficking. It regulates degradative endocytic trafficking and is required for the abscission step in cytokinesis, likely in the context of PI3KC3-C2.
It also plays a role in transporting lysosomal enzyme precursors from early to late endosomes.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.