Thermo Fisher Scientific RET Recombinant Rabbit Monoclonal Antibody (3U8T6)
RET 단백질을 인식하는 재조합 토끼 단일클론 항체로, 인간·마우스·랫트 반응성이 있음. Western blot, ICC/IF, ELISA에 적합하며 고순도 Affinity chromatography로 정제됨. 액상 형태로 -20°C 보관, 연구용으로 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3U8T6 |
| Immunogen | A synthetic peptide corresponding to amino acids 1000–1100 of human RET (NP_066124.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094200 |
Product Specific Information
Immunogen sequence:
DISKDLEKMM VKRRDYLDLA ASTPSDSLIY DDGLSEEETP LVDCNNAPLP RALPSTWIEN KLYGMSDPNW PGESPVPLTR ADGTNTGFPR YPNDSVYANW M
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation by cytogenetic rearrangement. It transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia types IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described but their biological validity has not been confirmed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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