Thermo Fisher Scientific COPB2 Recombinant Rabbit Monoclonal Antibody (1X5F7)
COPB2 단백질을 인식하는 Thermo Fisher의 재조합 토끼 단클론 항체. Western blot과 ELISA에 적합하며, 높은 특이성과 재현성을 제공. HEK293 세포에서 발현된 IgG 형 항체로, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:3,000–1:20,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1X5F7 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 657–906 of human COPB2 (NP_004757.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3093905 |
Product Specific Information
Immunogen sequence:
AYQLAVEAES EQKWKQLAEL AISKCQFGLA QECLHHAQDY GGLLLLATAS GNANMVNKLA EGAERDGKNN VAFMSYFLQG KVDACLELLI RTGRLPEAAF LARTYLPSQV SRVVKLWREN LSKVNQKAAE SLADPTEYEN LFPGLKEAFV VEEWVKETHA DLWPAKQYPL VTPNEERNVM EEGKDFQPSR STAQQELDGK PASPTPVIVA SHTANKEEKS LLELEVDLDN LELEDIDTTD INLDEDILDD
Target Information
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non–clathrin-coated vesicles, mediating biosynthetic protein transport from the ER through the Golgi to the trans-Golgi network.
Coatomer complex is required for budding from Golgi membranes and is essential for retrograde Golgi-to-ER transport of dilysine-tagged proteins.
In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), small GTP-binding proteins. The complex also influences Golgi structural integrity and the processing, activity, and endocytic recycling of LDL receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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