Thermo Fisher Scientific COPB2 Recombinant Rabbit Monoclonal Antibody (1X5F7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:3,000-1:20,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

1X5F7

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 657-906 of human COPB2 (NP_004757.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:COPB2,uniProtId:P35606-1,ncbiNodeId:9606,antigenRange:657-906,antigenLength:906,antigenImageFileName:MA5-51300_COPB2_P35606-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51300_COPB2_P35606-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3093905

Product Specific Information

Immunogen sequence: AYQLAVEAES EQKWKQLAEL AISKCQFGLA QECLHHAQDY GGLLLLATAS GNANMVNKLA EGAERDGKNN VAFMSYFLQG KVDACLELLI RTGRLPEAAF LARTYLPSQV SRVVKLWREN LSKVNQKAAE SLADPTEYEN LFPGLKEAFV VEEWVKETHA DLWPAKQYPL VTPNEERNVM EEGKDFQPSR STAQQELDGK PASPTPVIVA SHTANKEEKS LLELEVDLDN LELEDIDTTD INLDEDILDD

Target Information

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.