Thermo Fisher Scientific Phospho-ErbB2 (HER-2) (Tyr1248) Polyclonal Antibody
Phospho-ErbB2 (HER-2) (Tyr1248) 폴리클로날 항체로, 인산화된 HER2 단백질 검출에 적합합니다. IHC(Paraffin)에서 1:50 희석으로 사용 가능하며, 열 매개 항원 회복을 권장합니다. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관이 필요합니다.
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Thermo Fisher Scientific Phospho-ErbB2 (HER-2) (Tyr1248) Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from the region of human c-erbB2 that contains phosphorylated tyrosine 1248 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549815 |
Product Specific Information
Heat-mediated antigen retrieval is recommended prior to staining, using a 10 mM citrate buffer (pH 6.0) for 10 minutes followed by cooling at room temperature for 20 minutes.
Following antigen retrieval, incubate samples with primary antibody for 30 minutes at room temperature.
A suggested positive control is breast carcinoma.
Target Information
ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors.
Herceptin, used in treatment of metastatic Her2-positive cancer, is a monoclonal antibody targeting this kinase.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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