Thermo Fisher Scientific CXCR1 Monoclonal Antibody (501)
CXCR1 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, Immunofluorescence, Flow cytometry에 적합합니다. Human 시료 반응성이 있으며, Protein A/G로 정제된 액상형 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
| Flow Cytometry (Flow) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 501 |
| Immunogen | Synthetic peptide corresponding to the N-terminal residues 5–19 of human CXCR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 1 mg/mL BSA, 30% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2637106 |
Product Specific Information
MA1-206 detects CXCR1/IL8RA from human samples.
It has been successfully tested in western blot, immunofluorescence, and flow cytometry applications.
In western blot, MA1-206 detects CXCR1/IL8RA (human) at an approximate molecular weight of 30 kDa.
Target Information
CXCR1 is a member of the G-protein-coupled receptor family and functions as a receptor for interleukin 8 (IL8).
It binds IL8 with high affinity and transduces signals through a G-protein activated second messenger system.
Knockout studies in mice suggest that CXCR1 inhibits embryonic oligodendrocyte precursor migration in the developing spinal cord.
This gene, IL8RB (another high-affinity IL8 receptor), and IL8RBP (a pseudogene of IL8RB) form a gene cluster in the chromosome region 2q33–q36.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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