Thermo Fisher Scientific CXCR1 Monoclonal Antibody (501)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Flow Cytometry (Flow)

1:100-1:1,000

-

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

501

Immunogen

Synthetic peptide corresponding to the N-terminal residues 5-19 of human CXCR1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CXCR1,uniProtId:P25024-1,ncbiNodeId:9606,antigenRange:5-19,antigenLength:350,antigenImageFileName:MA1-206_CXCR1_P25024-1_House_mouse.svg,antigenImageFileNamePDP:MA1-206_CXCR1_P25024-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 1mg/mL BSA, 30% glycerol

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2637106

Product Specific Information

MA1-206 detects CXCR1/IL8RA from human samples.

MA1-206 has been successfully tested in western blot, immunofluorescence and flow cytometry applications. In western blot, MA1-206 detects CXCR1/IL8RA (human) at approximate molecular weight of 30 kDa.

Target Information

CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.