Thermo Fisher Scientific OAS2 Monoclonal Antibody (OTI5C10), TrueMAB
OAS2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 적합합니다. 인간 유래 OAS2(aa 60-335) 재조합 단백질을 면역원으로 제작되었습니다. 동결건조 형태로 제공되며, PBS 완충액(8% 트레할로스) 내 보존 및 -20°C 보관이 권장됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 60–335 of human OAS2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The OAS2 gene encodes a member of the 2-5A synthetase family, key proteins in the innate immune response to viral infection. These proteins are induced by interferons and use ATP in 2′-specific nucleotidyl transfer reactions to synthesize 2′,5′-oligoadenylates, which activate RNase L. This leads to viral RNA degradation and inhibition of viral replication. The gene family members are clustered on chromosome 12, with multiple alternatively spliced isoforms reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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