Thermo Fisher Scientific TRIM24 Monoclonal Antibody (OTI2D9), TrueMAB
TRIM24 단백질을 인식하는 Mouse monoclonal 항체로 Western blot과 IHC(Paraffin)에서 검증됨. Human 시료에 반응하며 carrier-free 형태로 제공. 동결건조 상태로 보관이 용이하고, 재구성 후 약 1 mg/mL 농도로 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 706–1016 of human TRIM24 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The TRIM24 protein mediates transcriptional control through interaction with the activation function 2 (AF2) region of several nuclear receptors, including estrogen, retinoic acid, and vitamin D3 receptors.
It localizes to nuclear bodies and associates with chromatin and heterochromatin-related factors.
TRIM24 belongs to the tripartite motif (TRIM) family, characterized by three zinc-binding domains (RING, B-box type 1, B-box type 2) and a coiled-coil region.
Two alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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