Thermo Fisher Scientific CRYGD Monoclonal Antibody (2H3)
CRYGD 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 2H3). Western blot과 ELISA에 사용 가능하며, 높은 특이성과 안정성을 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.03 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H3 |
| Immunogen | CRYGD (NP_008822, 75–174 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SVRSCRLIPH SGSHRIRLYE REDYRGQMIE FTEDCSCLQD RFRFNEIHSL NVLEGSWVLY ELSNYRGRQY LLMPGDYRRY QDWGATNARV GSLRRVIDFS
Target Information
Crystallins are separated into two classes: taxon-specific (enzyme) and ubiquitous. The ubiquitous class constitutes the major proteins of vertebrate eye lens and maintains lens transparency and refractive index.
Lens central fiber cells lose their nuclei during development, so crystallins are synthesized and retained throughout life, making them extremely stable proteins.
Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins belong to a superfamily.
Gamma-crystallins are monomeric, highly symmetrical proteins lacking connecting peptides and terminal extensions.
They are differentially regulated after early development.
Four gamma-crystallin genes (γA–γD) and three pseudogenes (γE–γG) form a genomic cluster.
Mutations or aging-related changes in these genes have been implicated in cataract formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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