Thermo Fisher Scientific CRYGC Monoclonal Antibody (7C4)
Thermo Fisher Scientific의 CRYGC 단일클론 항체(7C4)는 인간 CRYGC 단백질을 인식하는 Mouse IgG2a 형 항체로, Western blot과 ELISA에 적합합니다. 액상 형태이며 PBS buffer에 보존되어 연구용으로 안정적입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7C4 |
| Immunogen | CRYGC (NP_066269, 75–174 a.a) 부분 재조합 단백질, GST tag 포함 (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SIRSCCLIPQ TVSHRLRLYE REDHKGLMME LSEDCPSIQD RFHLSEIRSL HVLEGCWVLY ELPNYRGRQY LLRPQEYRRC QDWGAMDAKA GSLRRVVDLY
Target Information
Crystallins are separated into two classes: taxon-specific (enzyme) and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains its transparency and refractive index.
Since lens central fiber cells lose their nuclei during development, these crystallins are produced and retained throughout life, making them extremely stable proteins.
Mammalian lens crystallins are divided into alpha, beta, and gamma families, with beta and gamma crystallins forming a superfamily.
Gamma-crystallins are monomeric proteins typically lacking connecting peptides and terminal extensions, and are differentially regulated after early development.
Mutations or aging-related changes in gamma-crystallins have been implicated in cataract formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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