Thermo Fisher Scientific Synaptophysin Polyclonal Antibody
Synaptophysin 단백질을 인식하는 Rabbit Polyclonal Antibody로 신경말단 및 신경내분비 종양 마커 연구에 적합. WB 및 IHC에 사용 가능하며, 동결건조 형태로 제공. Rat 유래 합성 펩타이드 항원으로 제작되어 높은 특이성을 보유.
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Thermo Fisher Scientific Synaptophysin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from rat Synaptophysin conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Synaptophysin.
Target Information
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting involvement in synaptic vesicle endocytosis. It also plays a role in regulating short-term and long-term synaptic plasticity.
Synaptophysin is widely used as a marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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