Thermo Fisher Scientific SRY Monoclonal Antibody (1G4)
SRY 단백질을 인식하는 Mouse IgG1 단클론 항체로 인간 시료에 반응. WB, IHC, Flow, ELISA 등 다양한 응용 가능. 정제된 재조합 인간 SRY(aa 1–204)를 면역원으로 사용. 1 mg/mL 농도의 액상 형태로 단백질 G 정제됨.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G4 |
| Immunogen | Purified recombinant fragment of human SRY (amino acids 1–204) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538652 |
Product Specific Information
MA5-17181 targets SRY in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human SRY (amino acids 1–204) expressed in E. coli.
MA5-17181 detects SRY with a predicted molecular weight of approximately 23.9 kDa.
Target Information
This intronless gene encodes a transcription factor that belongs to the high mobility group (HMG)-box family of DNA-binding proteins.
The protein acts as the testis-determining factor (TDF), initiating male sex determination.
Mutations in this gene can result in XY females with gonadal dysgenesis (Swyer syndrome), and translocation of part of the Y chromosome containing this gene to the X chromosome can cause XX male syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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