Thermo Fisher Scientific Thrombopoietin Monoclonal Antibody (1B11)
인간 Thrombopoietin(THPO)을 표적하는 Mouse IgG2a 단클론 항체로, WB, Flow Cytometry, ELISA에 적합합니다. 고순도 Protein G 정제, 1 mg/mL 농도, 비결합형 액상 제품이며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B11 |
| Immunogen | Purified recombinant fragment of human THPO expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538659 |
Product Specific Information
MA5-17188 targets THPO in FACS, indirect ELISA, and WB applications, showing reactivity with Human samples.
The immunogen is a purified recombinant fragment of human THPO expressed in E. coli.
MA5-17188 detects THPO with a predicted molecular weight of approximately 37.8 kDa.
Target Information
Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) regulates platelet generation by acting on hematopoietic cells committed to the megakaryocyte lineage.
Binding of thrombopoietin to its receptor MPL (CD110) initiates signaling via JAK/STAT, MAPK, and PI3K/AKT pathways, leading to proliferation and differentiation of megakaryocytes and platelet production.
Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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