Thermo Fisher Scientific PD-L1 Recombinant Rabbit Monoclonal Antibody (OR-5E3), TrueRAB
PD-L1 단백질을 표적하는 재조합 토끼 단클론 항체로, 인간 시료에 반응합니다. 파라핀 포매 조직의 면역조직화학(IHC) 분석에 적합합니다. 고순도 친화 크로마토그래피 정제 및 안정적인 PBS/BSA/glycerol 저장 buffer를 사용합니다. 연구용 전용 제품입니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | OR-5E3 |
| Immunogen | Synthetic peptide within Human PD-L1 C-terminal (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. PD-L1 binds specifically to the programmed death receptor 1 (PD-1), which negatively regulates T-cell receptor (TCR) signaling. Upon PD-L1 binding, TCR-mediated proliferation and cytokine production are reduced. PD-L1 expression is abundant in many murine and human cancers and can be upregulated by IFN-gamma stimulation. Therefore, PD-L1 may play a crucial role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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