
Thermo Fisher Scientific PD-L1 Recombinant Rabbit Monoclonal Antibody (OR-5E4), TrueRAB
PD-L1 단백질을 타겟으로 하는 재조합 토끼 단일클론 항체. Western blot에 최적화되어 있으며, 인간 시료에 반응. 고순도 친화 크로마토그래피 정제, 안정적 액상 형태로 제공. 종양 면역 회피 연구에 적합.
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | OR-5E4 |
| Immunogen | Synthetic peptide within Human PD-L1 (amino acids 180–230). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. Its receptor, programmed death receptor 1 (PD-1), negatively regulates T-cell receptor (TCR) signaling. PD-L1 binding to PD-1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many human and murine cancers and can be upregulated by IFN-γ stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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