Thermo Fisher Scientific CRYAB Polyclonal Antibody
CRYAB 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot 및 ELISA에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제, 안정적인 PBS/glycerol 저장용액 포함.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–175 of human CRYAB (NP_0018761) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805524 |
Product Specific Information
- Immunogen sequence: MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFPT STSLSPFYLR PPSFLRAPSW FDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHR KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT AAPKK
- Positive Samples: U-87MG, 293T, A-549, Mouse brain, Mouse heart, Mouse kidney, Mouse lung, Rat heart
- Cellular Location: Cytoplasm, Nucleus
Target Information
Lens proteins consist almost entirely of crystallins (about 95%). Crystallins are also found in vertebrate skeletal muscle tissue. In the lens, their structural function is to assist in maintaining the proper refractive index. The mammalian lens contains three major classes of crystallins: alpha, beta, and gamma. Alpha-crystallin is the largest, composed of alpha-A and alpha-B gene products. In addition to maintaining the refractive index, alpha-crystallin acts as a chaperone to prevent aggregation leading to cataract formation. Phosphorylated alpha-crystallin responds to cellular stress and may play a role in protein maintenance. Alpha-B crystallin has been linked to Alexander’s disease, where it accumulates in brain cells.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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