Thermo Fisher Scientific UBXN2B Monoclonal Antibody (OTI1G9), TrueMAB
UBXN2B 단백질을 인식하는 마우스 단클론 항체로, Western blot과 유세포분석(Flow Cytometry)에 적합합니다. 고순도 친화 크로마토그래피 정제 제품이며, PBS/BSA/glycerol 완충액에 보관됩니다. 세포 내 소기관 생합성 연구용으로 최적화된 연구 전용 항체입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G9 |
| Immunogen | Full length human recombinant protein of human UBXN2B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.72 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
UBXN2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein containing one UBX domain and one SEP domain.
UBXN2B is required for ER and Golgi biogenesis and plays a role in their maintenance during interphase and reassembly at the end of mitosis.
Through interaction with VCP, UBXN2B forms a complex with membrane fusion activity. It functions as an adapter protein required for Golgi and endoplasmic reticulum biogenesis.
The complex formed with VCP has membrane fusion activity that requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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