Thermo Fisher Scientific Synaptophysin Polyclonal Antibody
Synaptophysin 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. Western blot 및 IHC(Paraffin) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 신경세포 시냅스 소포 마커 연구용으로 사용됩니다.
- 카탈로그번호
- 500-2174
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide of human Synaptophysin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human pancreas
- Cellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Target Information
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting involvement in synaptic vesicle endocytosis. It also plays a role in regulating short-term and long-term synaptic plasticity. Synaptophysin is widely used as a marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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