Thermo Fisher Scientific CD82 Polyclonal Antibody
CD82 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot과 IHC에 적합하며 인간 시료 반응성. 합성 펩타이드 항원을 기반으로 제작되어 높은 특이성과 안정성을 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 220–267 of human CD82 conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The antigen shares 93% identity with rat and mouse sequences.
- Specificity of this antibody: CD82.
Target Information
The CD82 metastasis suppressor gene product is a membrane glycoprotein belonging to the transmembrane 4 superfamily. Expression of this gene is downregulated during tumor progression in human cancers and can be activated by p53 through a consensus binding sequence in the promoter region. Expression of CD82 and p53 are strongly correlated, and loss of both proteins is associated with poor survival in prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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