Thermo Fisher Scientific TRPV4 (extracellular) Polyclonal Antibody
TRPV4 단백질의 외부영역을 인식하는 rabbit polyclonal 항체로, Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공되어 안정적 보관이 용이함.
- 카탈로그번호
- ACC-124-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TRPV4 (extracellular) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 2.5 µg |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)EDQSN(S)TVPSYPA(S)RD, corresponding to amino acid residues 647–662 of rat TRPV4, 3rd extracellular loop |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
- The antibody is shipped lyophilized at room temperature. Upon arrival, store at –20°C.
- Reconstituted solution can be stored at 4°C (protected from light) for up to 1 week.
- For long-term storage, aliquot and store at –20°C. Avoid repeated freeze-thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4)
TRPV4 is a cation-selective, Ca²⁺-permeable channel activated by osmotic and mechanical stimuli. It belongs to the OSM9-like transient receptor potential channel (OTRPC) subfamily within the TRP superfamily. TRPV4 plays a key role in osmotic pressure regulation and mechanosensitivity.
Mutations in the TRPV4 gene are associated with disorders such as spondylometaphyseal dysplasia, metatropic dysplasia, and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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