Thermo Fisher Scientific TRPM2 (extracellular) Polyclonal Antibody
TRPM2 단백질의 세포외 루프를 인식하는 Rabbit Polyclonal 항체로, WB, IHC(F), Flow Cytometry에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, Lyophilized 형태로 제공. 산화 스트레스 관련 이온 통로 연구에 적합.
- 카탈로그번호
- ACC-128-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TRPM2 (extracellular) Polyclonal Antibody
Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:200 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Flow Cytometry (Flow) | 2.5 µg | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)NGTDPYKPK(S)PESD, corresponding to amino acid residues 999–1012 of human TRPM2, 3rd extracellular loop |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on the sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquots should be kept at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
TRPM2 belongs to the ion transport protein family, including sodium, potassium, and calcium ion channels.
This family features proteins with six transmembrane helices, where the last two flank a loop determining ion selectivity.
TRPM2 is activated by oxidative stress and contributes to cell death susceptibility.
It is a calcium-permeable cation channel regulated by free intracellular ADP-ribose.
Several alternatively spliced transcript variants of TRPM2 have been described, but their full-length nature remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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