Thermo Fisher Scientific BID Monoclonal Antibody (21F10)
BID 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체(21F10)입니다. Western blot, ELISA, Immunoprecipitation 등에 사용 가능하며, 고순도 액상 형태로 제공됩니다. 세포 사멸 연구 및 BCL-2 패밀리 단백질 분석에 적합합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific BID Monoclonal Antibody (21F10)
Thermo Fisher Scientific BID Monoclonal Antibody (21F10)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 2 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 21F10 |
| Immunogen | Recombinant human protein purified from E.coli (His-Bid) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1954920 |
Product Specific Information
A suggested positive control for this product is A431 cells.
Target Information
BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. Bid is a member of the BCL-2 family of cell death regulators. BID mediates mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this protein, and the COOH-terminal part translocates to mitochondria, triggering cytochrome c release.
BID exists in an inactive form in living cells and becomes cleaved and activated by caspase 8 in response to TNF alpha or Fas ligand. Once cleaved, the C-terminal 15 kDa fragment (p15) translocates to mitochondria, sufficient to trigger cytochrome c release and induce apoptosis.
BID serves as a direct molecular link between caspase 8 activation and mitochondrial death machinery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.