Thermo Fisher Scientific ERK1 Monoclonal Antibody (33A5)
ERK1 단백질을 인식하는 Thermo Fisher Scientific의 Mouse monoclonal antibody (Clone 33A5). Western blot 및 ELISA에 적합하며, 293T 세포를 양성 대조군으로 권장. MAPK 신호전달 경로 연구에 활용 가능.
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- pk
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Thermo Fisher Scientific ERK1 Monoclonal Antibody (33A5)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 33A5 |
| Immunogen | Recombinant human protein purified from E.coli (His-Erk1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1957651 |
Product Specific Information
A suggested positive control for this product is 293T cells.
Target Information
MAPK3 (ERK1) is a serine/threonine kinase that acts as an important activator of p90, RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.
ERK1 is widely expressed and regulates meiosis, mitosis, and post-mitotic functions in differentiated cells.
Various stimuli—such as growth factors, cytokines, viral infection, G protein-coupled receptor ligands, and transforming agents—activate ERK1 and ERK2 pathways.
Functionally, ERK1 participates in a signaling cascade that controls cellular processes including proliferation, differentiation, and cell cycle progression in response to extracellular signals.
ERK1 is activated by upstream kinases and translocates to the nucleus to phosphorylate nuclear targets.
Alternatively spliced transcript variants encoding different isoforms of ERK1 have been described.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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